期刊文献+

粘质沙雷菌菌苗预防尖锐湿疣复发的疗效观察 被引量:2

Observatiou of the Preventive Effect of Serratia Marcescens Vaccine on Relapse of Condyloma Accuminatum
下载PDF
导出
摘要 目的 探讨粘质沙雷菌菌苗预防尖锐湿疣复发的作用及机理。方法 尖锐湿疣患者经微波治疗后肌注粘质沙雷菌菌苗。结果  3个月时 ,其复发率明显低于单纯用微波治疗的对照组。结论 粘质沙雷菌菌苗对尖锐湿疣的复发有预防作用 。 Objective To investigate the preventive effect of serratia marcescens vaccine on relapse of condyloma accuminatum and its mechanism.Methods Giving the patients intramuscular injections of serratia marcescens vaccine after the treatments of the microwave instrument.Results Four months later,the difference of the relapse rate between the serratia marcescens vaccine treated group and the control group was significant.Conclusion Serratia marcescens vaccine has evidently preventive effect on preventing relapse of condyloma accuminatum,improvement of the immune system might play an important role in its mechanism.
机构地区 海军
出处 《中国皮肤性病学杂志》 CAS 北大核心 2002年第5期321-322,共2页 The Chinese Journal of Dermatovenereology
关键词 粘质沙雷菌菌苗 预防 尖锐湿疣 复发 疗效观察 Serratia marcescens vaccine(SMV) Condyloma accuminatum(CA)
  • 相关文献

参考文献3

二级参考文献7

  • 1靳小青 何晓文 等.抗癌新药S311抗癌菌苗的研究[J].中国新药杂志,1996,6(5):336-336.
  • 2朱允中 史鹤玲.治疗用II期临床研究[J].治疗用S311抗菌苗审报资料,1999,:9-9.
  • 3何晓文 靳小青 等.S311菌苗对动物细胞免疫功能的影响[J].海军军事医学,1999,18(3):14-14.
  • 4金一平,上海免疫学杂志,1994年,14卷,5页
  • 5富宁,中国免疫学杂志,1991年,7卷,278页
  • 6田渭涛,中华微生物学和免疫学杂志,1987年,7卷,73页
  • 7靳小青,杨其库,陆翠琴,何小文.抗癌新药S311菌苗药理药效学研究[J].海军医学杂志,1996,14(4):345-349. 被引量:5

共引文献43

同被引文献23

  • 1许冰,瞿国伟,俞运彪,张丽娟.尖锐湿疣血清肿瘤坏死因子和白介素2水平的观察[J].中华皮肤科杂志,1996,29(3):190-191. 被引量:22
  • 2Tobery TW,Smith JF,Kuklin Net al. Effect of vaccine delivery system on the induction of HPV16L1-specific humoral and cell-mediated immune responses in immunized rhesus macapques[J]. Vaccine ,2003,21( 13-14) : 1539-1547.
  • 3Moniz M,Ling M,Hung CF et al. HPV DNA vaccine[J]. Front Biosci ,2003,8: 55-68.
  • 4Koutsky LA, Ault KA, Wheeler CM et al. Acontrolled trial of a human papillomavirus type 16 vaceine[J].N gngl J Med,2002,342(21):164541651.
  • 5Pearson GW, Langley RG. Topical imiquimod [J]. J Dermatolog Treat, 2001,12 ( 1 ) : 37440.
  • 6Sauder DN. Immunomodulatory and pharmacologic properties of imiquimod [J]. J Am Acad Dermatol,2000,43(142) :6411.
  • 7Gruber PC,Wilkinson J. Successful treatment of perianal warts in a child with 5% imiquimod cream[J].J Dermatolog Treat ,2001,12(4) :215-217.
  • 8Vilata JJ,Sierra X. Efficacy of imiquimod 5 % creamin treating genital and perianal warts [J]. Ann Dermatol Venerol, 2002,129 : 322.
  • 9Frazer I. Vaccines for papillomavirus infection[J].Virus Res,2002,89(21):271-274.
  • 10Koutsky La, Kiviat NB. Genital human papillomavirus. In : Holmes KK, Sparling PK, Mardh PA et al. Sexually transmitted diseases [M]. 3rd. Xian:World Publishing Corporation, 1999. 347-359.

引证文献2

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部