摘要
利用盐酸林可霉素在丁醇、水中溶解特性及丁醇与水可共沸的特性,改变丙酮法结晶的工艺条件,通过丁醇结晶法,使盐酸林可霉素的收率和质量有了较大提高。
A new crystallization method of lincomycin hydrochloride for industrial production was introduced using butanlo azeotrapy technology, the yield and quality of product was higher, and the cost was lower.
出处
《黑龙江医药》
CAS
2002年第5期355-356,共2页
Heilongjiang Medicine journal
关键词
盐酸林可霉素
结晶
共沸
工艺
lincomycin hydrochloride
crystallization
butanol azeotropy technoloy
