应用脉冲多普勒观察慢性心衰心脏舒张功能和氨利酮的治疗干预作用

OBSERVATION OF HEART DIASTOLIC FUNCTION USING PULSED DOPPLER ECHOCARDIOGRAPHY FOR CHRONIC HEART FAILURE AND INTERFERENCE OF TREATMENT USING AMRINONE

用国产口服氨利酮.对10例慢性充血性心力衰竭患者,用脉冲多普勒超声心动图观察了用氟利酮前和72小时后的二尖瓣舒张期血流频谱.结果发现:反映左室被动充盈过程的舒张晚期血流峰值速度(A峰)有较大下降,反映左室舒张功能的A峰/E峰比值显著降低;说明了左室舒张功能的改善.舒张早期减速度有较大增加;它也是左室舒张功能的指标之一。

China-made amrinone (AMR) was orally administered to 10 patients with chro- nic congestive heart failure(CHF) for 72 hours, its mitral valve blood flow spectral shift was observed by pulsed Doppier echocardiograp hy(PDE). We found that peak A decreased, and peak A/peak E ratio decreased significantly. It suggested that AMR could improve left ventricular diastolic function. Early diastolic drag acceleration increased, it is one index of left ventricular diastolic function, its elevation suggested that left ventricular diastolic function had some improvement. These observation suggested that AMR could improve left ventricular diastolic function for hypertensive heart disease, coronary artery disease, congestive cardiom-yopathy with limited left ventricular diastolic function