子宫收缩抑制剂用于前置胎盘的期待治疗

Expectant treatment of placenta previa with depressant of uterine contraction

目的 :探讨子宫收缩抑制剂用于前置胎盘期待治疗的效果、副作用和围产儿结局。方法 :将 5 0例未足月前置胎盘孕妇分为两组。治疗Ⅰ组 3 0例 ,采用硫酸镁加舒喘灵 (沙丁胺醇 )治疗 ;治疗Ⅱ组 2 0例 ,采用安宝 (利托君 )治疗。结果 :两组比较 ,治疗Ⅰ组延长孕期平均 2 7.0 0d ,治疗Ⅱ组延长孕期平均 3 0 .2 5d ,无统计学意义 (P >0 .0 5 )。治疗Ⅰ组新生儿出生体重平均2 45 6g ,新生儿Apgar评分平均 6.75分 ,治疗Ⅱ组新生儿出生体重平均 3 10 6g ,新生儿Apgar评分平均 9.12分 ,有统计学意义 (均为P <0 .0 0 1)。结论 :子宫收缩抑制剂用于前置胎盘期待治疗效果好、安全。治疗Ⅱ组围产儿结局优于Ⅰ组。

Objective To investigate the effectiveness,side effect,outcome of perinatal infants of the expectant treatment in placenta previa with depressant of uterine contraction.Methods 50 wemen with placenta previa of preterm labor were assigned into two groups.30 patients treated with magnesium sulfate and salbutamol were served as study Ⅰ group.20 patients enrolled in the study Ⅱ group,receiving ritodrine.Results The study Ⅰ group prolonged the gestational period to an average of 27.00 days.The study Ⅱ group prolonged the gestational period to an average of 30.25 days.The difference of two groups had no significance( P >0.05).The study Ⅰ group increased the birth weight of newborn to an average of 2?456?g and Apgar score of newborn is 6.75.The study Ⅱ group increased the birth weight of newborn to an average of 3?106?g and Apgar score of newborn is 9.12 ( P <0.001).Conclusion Depressant of uterine contraction is highly effective and safe for expectant treatment of placenta previa.The outcome of perinatal infant of the study Ⅱ group is better than that of the study Ⅰ group.