弥漫性轴索损伤的生物力学机理

Biomechanical Mechanism of Diffuse Axonal Injury

弥漫性轴索损伤 (DAI)作为原发脑损伤的一种类型 ,有其特有的损伤机理。荷载性质 ,施载方式 ,颅脑颈各组织结构特性均与 DAI发生密切相关。本文从生物力学角度综述了荷载量、荷载波形、荷载作用时间、直线加速、旋转加速、直线 /旋转复合加速、脑组织、大脑镰小脑幕、颅骨、颈部对应力应变产生及分布的影响 ,及与

As one type of primary brain injury, diffuse axonal injury (DAI) has specific traumatic mechanisms. The occurence of DAI is close to the loading property, loading manner, structural characteristics of skull, brain tissue and neck. This article demonstrated how the stress and strain varied in brain tissue effected by the load magnitude, load waveform, load frequency, load duration, linear acceleration, rotational acceleration, compounded linear/rotational acceleration, brain tissue, cerebral falx, cerebellar tentorium, skull and neck, and what are the relationships between these factors and the event of DAI.