肝脏中死亡受体的生物学和病理生物学作用

Biology and Pathobiology of Death Receptors in Liver

死亡受体通过细胞内信号传导途径可诱导细胞凋亡 ,与机体的生长、发育、病变和死亡有关。本文对新近研究发现的死亡受体的种类、结构特征及其诱导细胞凋亡的机理进行了综述 。

Death receptors induce apoptosis by intracellular signaling transmission and relate to body growth, development, disease and death. This paper reviews the structural character of death receptors, and the mechanisms by which apoptosis is induced. The biology and pathobiology of these death receptors in liver are discussed as well.