摘要
目的通过双能源X线吸收测定法,监测短期肠外营养支持对不同状况患者机体组成改变的影响。方法58例患者分三组,第一组为16例轻度营养不良或正常营养状况的炎性肠道疾病患者,接受2周肠外营养(PN)支持,热量105kJ/(kg·d),氮量为0.2g/(kg·d);第二组为24例中等程度以上营养不良的慢性肠梗阻或肠瘘患者,平均接受PN支持时间为(14.6±4.2)d,摄入热量和氮量与第一组相同;第三组为18例中等程度以上营养不良患者,疾病种类同第二组,平均接受PN支持时间为(15.2±3.8)d,摄入热量134.4～147kJ/(kg·d),氮量为0.25g/(kg·d)。机体组成测定应用HologicQDR-2000双能源X线测定仪。结果第一组患者在2周PN后,机体各组成成分无明显改变(P>0.05)。第二、三组患者在2周PN后,体重增加,体脂及瘦组织群均有不同程度恢复,尤其以体脂增加更为明显(P<0.01)。肠外营养支持时,营养不良患者的体脂及瘦组织群增加程度与摄入的热量与氮量明显相关(r=0.78,P<0.01)。结论短期肠外营养支持对营养正常或轻度营养不良患者的机体组成无明显影响,但可增加中、重度营养不良患者体重、体脂及瘦组织群含量,尤以体脂增加更为明显。营养不良患者的体脂及瘦组织群增加程度与摄入的热量与氮量明显相关。
Objective To evaluate the effects of parenteral nutrition support on body composition of malnou-rished patients by dual-energy X-ray absorptiometry(DEXA).Methods Body composition was measured by DEXA,these measurements were repeated in58malnourished patients after two weeks of total parenteral nutrition support with105～147kJ/(kg·d)of calorie and0.2～0.25g/(kg·d)of nitrogen.Results After PN support,the body weight of the moderately and severely malnourished patients increased by(3.8±1.1)kg (P<0.05).Weight gain was accompanied by an increase in fat tissue(2.5±0.8)kg and lean body mass (1.4±0.4)kg.There were nonsignificant increase in body weight,fat mass and lean body mass in normal nutritional status subjects.Conclusion With modest nutritional repletion,proportionate gains in body compartments were possible.DEXA could be used to monitor the changes of body composition in patients during refeeding.
出处
《中国临床营养杂志》
2002年第3期152-155,共4页
Chinese Journal of Clinical Nutrition
