外周型胆管癌的外科手术治疗(附45例报告)

Surgical Treatment of Peripheral Intrahepatic Cholangiocarcinoma (A Report of 45 Cases)

目的 :探讨外周型胆管癌的外科治疗。方法 :对 45例外周型胆管癌病人进行了手术治疗 ,并对其临床病理特征、生物学指标、手术结果和生存率进行了分析。结果 :根治性手术有 34例 ,姑息性手术有 11例 ,根治性手术病人1年～ ,3年～ ,5年～生存例数分别为 2 4例 ,占 70 % ;15例 ,占 44 % ;8例 ,占 2 4%。姑息性手术病人 1年～ ,3年～ ,5年～生存例数分别为 3例 ,占 2 7% ;1例 ,占 9% ;0。根治性手术病人 1年～ ,3年～ ,5年～生存率高于姑息性手术病人的生存率。结论 :根治性肝切除术能提高外周型胆管癌的生存率。

Objective: To investigate the surgical management in patients with peripheral intrahepatic cholangiocarcinoma.Methods:45 patients with peripheral intrahepatic cholangiocarcioma from 1994 to 2001 underwent Laparotomy.The clinicopathological features, biochemical markers,operative results,and survival rates of those cases were analyzed.Results:The operation was considered curative in 34 cases when three criteria were met:solitary liver Tumor,no lymph node invasion, and clearance margin of>1 cm.The others underwent palliative operation.The 1～,3～, and 5 year survival rates of the patients with curative resection were higher than that of patients with palliative resection.Conclusion:In selected patients, curative resection can be performed safely and is associated with long term survival.