低分子肝素钙治疗急性脑梗死的临床研究

Clinical Study of Low-molecular-weight Heparin Calcium Therapy on Acute Cerebral Infarction

目的 :观察低分子肝素钙治疗急性脑梗死的疗效及其对血液流变学、头颅CT的改善。方法 :治疗组和对照组各 63例均给予丹参注射液 2 5 0mL静滴、适当的脱水剂、脑保护剂及其他处理作为基础治疗 ,治疗组另给予低分子肝素钙 2 5 0 0抗Ⅹa国际单位腹部皮下注射 ,bid ,连续 10d为 1疗程。治疗前后分别作神经功能评分、头颅CT和血液流变学观察。结果 :治疗组神经功能恢复、头颅CT和血液流变学改善均明显优于对照组。结论

Aim:To study the efficacy of low molecular weight heparin calcium for treating acute cerebral infarction and the improvement of cranioncerebral CT and hemorrheology.Methods:63 cases of treatment group and 63 cases of control group were both treated with Salvia Miltiorrhiza (250 mL, iv) necessary dehydration agent, cerebral protective and other treatment measures, and the low molecular weight beparin calcium 2500 antibody Ⅹa(IU) was subcutaneously injected (b.i.d) to the cases of treatment group, and a course of treatment was 10 days. The score of neurological performance, cranioncerebral CT and hemodynamic change were observed before and after treatment. Results:The neurological acuity, cranioncerebral CT and hemodynamic change of cases of treatment group were apparently better than those of control group. Conclusion:the earlier treatment of acute cerebral infarction with low molecular weight heparin calcium on patients is safe and efficient