一期切除手术在治疗结肠癌导致急性肠梗阻患者的临床效果

Issue of excision surgery in the treatment of colon cancer,lead to the clinical effect of patients with acute intestinal obstruction

目的探讨手术一期切除在治疗结肠癌导致急性肠梗阻患者的临床效果。方法采用回顾性方法选取2012年3月-2014年5月在我院接受手术治疗的70例结肠癌引起急性肠梗阻的患者为研究对象,根据患者术式的不同,分为观察组和对照组,每组各35例。其中,观察组给予一期切除吻合术,对照组给予结肠次全切。比较两组患者术中出血量、手术时间、术后一个月并发症发生率、C-反应蛋白、中性粒细胞和D-二聚体含量的差异、手术前后1个月CEA、CA72-4和CA125水平的变化。结果观察组患者术中出血量及手术时间均较对照组少,差异具有统计学意义(P<0.05);观察组患者CEA、CA72-4和CA125水平较对照组明显降低。结论一期切除手术在治疗结肠癌导致急性肠梗阻方面能有效地降低术中出血量,减少并发症的发生,在缓解肠梗阻的同时,确保了结肠癌的根治。

Objective To investigate the issue of surgery in the treatment of colon cancer led to clinical effect in patients with acute intestinal obstruction. Methods 70 cases patients in our hospital with colon cancer and acute intestinal obstruction from March 2012 to May 2014 were chosen for the research. According to different surgical,patients were divided into two groups,35 cases in each group. Bleeding and operative time were compared between the two groups' patients; one month before and after surgery,the postoperative complication rate,surgery leukocyte and neutrophil of the two groups were also compared. The level of C- reactive protein,neutrophil and D- dimer were compared pre- operative and postoperative. Compared the level of colon cancer tumor markers CEA,CA72- 4 and CA125 levels of the two groups. Results The blood loss and operative time of observation group patients less than those in the control group,the difference was statistically significant(P < 0. 05); the level difference between the two groups of patients before surgery tumor markers had no statistically significant,after a month,the level of?? CEA,CA72- 4 and CA125 of observation group were significantly lower than the control group. Conclusions The first phase of surgery in the treatment of colon cancer led to acute intestinal obstruction aspect can effectively reduce blood loss,reduce the incidence of complications,intestinal obstruction at ease while ensuring a colon cancer cure.