射频消融术联合SOX方案治疗结直肠癌术后肝转移的疗效观察

目的综合分析射频消融术联合SOX(替吉奥+奥沙利铂)方案治疗结直肠癌术后肝转移的临床治疗效果,为治疗结直肠癌术后肝转移患者提供科学的数据参考。方法选取本院在2013年9月-2015年10月间收治的30例结直肠癌术后肝转移患者,按照不同的治疗方法随机分为观察组与对照组,两组均15例。观察组应用射频消融术联合SOX的方法,对照组应用SOX的治疗方法。结果观察组疾病控制率以及总有效率分别为86.67%(13/15)、73.33%(11/15),对照组疾病控制率以及总有效率分别为60.0%(9/15)、46.67%(7/15),观察组的疾病控制率以及总有效率远远高于对照组,数据比较差异有统计学意义(p<0.05)。结论射频消融术联合SOX方案治疗结直肠癌术后肝转移的临床治疗效果远远优于单纯SOX治疗效果。

Objective purpose: The efficacy of comprehensive analysis of radiofrequency ablation combined with Sox(s- 1) oxaliplatin regimen in the treatment of colorectal cancer liver metastasis,the treatment of colorectal cancer with liver metastases after provide scientific reference data. method: Select the hospital in September 2013 October 2015 were 30 cases of postoperative colorectal cancer patients with liver metastasis,according to the different treatment were randomly divided into observation group and control group,15 cases in two groups. Observation group was treated with radiofrequency ablation combined with Sox. Control group was treated with Sox treatment method. result: The observation group disease control rate and the total effective rate was 86. 67%(13/15),73. 33%(11/15) and the control group,the disease control rate and total effective rate were 60. 0%(9/15),46. 67%(7/15). In the observation group,the disease control rate and total efficiency is much higher than that of the control group,the difference between the data with statistical significance(P < 0. 05). conclusion: The clinical effect of radiofrequency ablation combined with SOX regimen in the treatment of liver metastasis after colorectal cancer surgery is far superior to the simple SOX treatment.