臭氧治疗慢性乙型肝炎肝纤维化的临床效果及对胃肠道的影响

Effect of ozone on hepatic fibrosis in patients with chronic hepatitis Band its effect on gastrointestinal tract

目的观察医用臭氧治疗乙型肝炎肝纤维化及代偿期肝硬化的临床疗效。方法 76例乙型肝炎肝纤维化及代偿期肝硬化患者随机分为臭氧治疗组(36例)和对照组(40例)。臭氧治疗组在基础治疗联合医用臭氧自血疗法3个月;对照组患者采用基础治疗,包括常规保肝降酶药物和抗病毒等方法。结果治疗3个月两组患者在症状方面均得到明显改善,臭氧治疗组优于对照组(P<0.05),在改善肝功能,肝纤维化血清学指标方面,治疗组均优于对照组(P<0.05)。两组均未出现严重的胃肠道不良反应。结论臭氧联合基础治疗对乙型肝炎肝纤维化及代偿期肝硬化患者具有改善症状、促进肝功能及肝纤维化指标恢复。

Objective To observe the clinical curative effect of the medical ozone therapy on hepatitis B liver fibrosis and decompensated cirrhosis of the liver Method 76 cases of hepatitis B liver fibrosis and decompensated cirrhosis patients are randomly divided into ozone treatment group(36 cases) and control group(40 cases).Ozone treatment group used basic treatment combined with ozone autohemotherapy for 3 months;the control group used the basic treatment,including the routine liver protection and enzyme reduction drugs,antiviral treatment,etc.Results After 3 months treatment,both the two groups patients' symptom has obviously improved,and the ozone group are superior to the control group(P<0.05).In improving liver function and liver fibrosis serological indexes,the treatment group is superior to the control group(P<0.05).Conclusions For the patients with hepatitis B liver fibrosis and decompensated cirrhosis,ozone combined basic treatment can improve symptom,promote the recovery of liver function and liver fibrosis indexes