新疆民丰县黑热病血清流行病学调查

Seroepidemiological survey and analysis of kala-azar in Minfeng County of Xinjiang

目的调查塔里木盆地南部和田地区民丰县黑热病流行状况。方法以r K39免疫层析法和r K39-ELISA夹心法检测人群黑热病抗体,阳性标本复测反应滴度,B超仪检测黑热病抗体阳性者脾脏。结果 5个乡镇检测7~9岁学生1 060人和成年村民49人,县城和地势较高的叶亦克乡未检出黑热病抗体阳性者,地处荒漠腹地的亚瓦通古孜、安迪尔和萨勒吾则克3个乡,学生的阳性率分别为8.00%(2/25)、1.83%(3/164)和0.76%(2/266),亚瓦通古孜乡成年村民的阳性率为8.16%(4/49);B超检查11份黑热病抗体阳性者(女5份和男6份)均未见脾脏肿大。结论调查塔里木盆地南部和田地区民丰县,新发现地处荒漠腹地的安迪尔乡和萨勒吾则克乡也有黑热病流行。

Objective To investigate epidemic of kala-azar in Minfeng County of Hotan Prefecture in southern Tarim Basin, Xinjiang, China. Methods r K39 dipsticks and r K39-ELISA were taken to detect antibodies of kala-azar in people. The positive specimens were retested response titer. Spleen of people with positive antibody to kala-azar was detected by B ultrasonic scanner. Results In the five townships, 1 060 students at age of 7 to 9 year-old and 49 adult villagers were detected.There was no detected positive antibody to kala-azar in Yeyike township with higher sea level and the county. In the hinterland of the desert, the positive rate of the students was 1.83%(3/164) in Andier township, 0.76%(2/266) in Saleuzek township, and 8.00%(2/25) in Yawatongguzi township where the positive rate of adult villagers was 8.16%(4/49). There was no swelling spleen detected in 11 people with positive antibody to kala-azar(5 women and 6 men). Conclusions It is newly found that there is epidemic of kala-azar both in Andier and Saleuzek township located in the hinterland of the desert in Minfeng County of Hotan in southern Tarim Basin, Xinjiang, China.