Clinical Investigation of Radiation Retinopathy Fundus and Fluorescein Angiographic Features

Purpose:To investigate the fundus and fluorescein angiographic features in the patients with radiation retinopathy.Clinical Materials:Color fundus photography and/or fluorescein angiography from 13 patients with nasopharyngeal carcinomas received external beam radiation were retrospectively analyzed.Reslts:In this study,26 damaged eyes of 13 patients eveloped some degree of radiation retinopathy.The earliest and most common finding was macular microvascular changes (microaneurysms and/or telangiectasia),which was observed in 100%(26/26)of the eyes.Intraretinal hemorrhages,macular capillary nonperfusion,and macular edema were noted in 84%,50%,and 42% of the eyes,respectively.Conclusions:Radiation retinopathy is common after external beam radiation of nasopharyngeal carcinomas.The prominent changes include maular microvascular changes,intraretinal hemorrhages and macular capillary nonperfusion.

Purpose: To investigate the fundus and fluorescein angiographic features in the patients with radiation retinopathy. Clinical Materials: Color fundus photography and/or fluorescein angiography from 13 patients with nasopharyngeal carcinomas received external beam radiation were retrospectively analyzed. Results: In this study, 26 damaged eyes of 13 patients developed some .degree of radiation retinopathy. The earliest and most common finding was macular microvascular changes (microaneurysms and/or telangiectasia), which was observed in 100% (26 / 26) of the eyes. Intraretinal hemorrhages, macular capillary nonperfusion, and macular edema were noted in 84% , 50% , and 42% of the eyes, respectively. Conclusions: Radiation retinopathy is common after external beam radiation of nasopharyngeal carcinomas. The prominent changes include macular microvascular changes, intraretinal hemorrhages and macular capillary nonperfusion. Eye Science 1999; 15: 183 - 186.