前列腺偶发癌的病理诊断及鉴别

Pathologic diagnosis and identification of IDPC

目的 探讨前列腺偶发癌与前列腺增生 (BPH)及前列腺腺癌的关系及鉴别诊断。方法 术后标本中 ,发现前列腺偶发癌 (IDPC) 32例。其中用开放手术标本诊断率为 2 % (8/ 4 0 9) ,用经尿道电切方法诊断率为 7.2 % (2 4 / 311) ,病理诊断均为腺癌。结果 手术方法与IDPC的诊断密切相关 ,IDPC的发病率伴随BPH逐年同步增加。结论 IDPC与BPH同源 ,是BPH腺体的局部恶变 ,部分临床癌是IDPC恶化的结果。

Objective To discuss the relationship between IDPC and BPH and that between IDPC and prostate adenocarcinoma, and the diagnosis and inentification of IDPC.Methods 32 cases of IDPC were found in post\|operation samples, by means of open operation , a diagnosis rate of 2% (8/409) ; the diagnosis rate of IDPC rose to 7.2% (24/311) by means of transurethral route galvano\|prostatotomy. All the 32 cases were diagnosed pathologically as adenocarcinoma.Results Operation method are closely related to the diagnosis of IDPC , and the incidence rate of IDPC increases synchronously year by year with BPH .Conclusion IDPC and BPH are isogeneric: IDPC results from the local malignisation of BPH glands while some clinical cancers stem from the malignisation of IDPC .