复发性星形细胞瘤恶性进展过程的临床研究

Progressive study of recurrent astrocytic tumor

目的 探讨复发性星形细胞瘤恶性进展与年龄、组织类型和病理分级的关系。方法 对 5 4例复发性星形细胞瘤两次住院手术的临床和病理资料进行统计分析。结果 成人组星形细胞瘤复发间期明显低于青少年组 ,且复发时恶性程度有增加趋势 ,其中间变性星形组织和肥胖细胞型星形细胞瘤复发时恶性程度往往增加 ,分别占首次发病例数的 77.8%和 78.6 %。结论 星形细胞瘤恶性进展与年龄、肿瘤的病理分级和组织类型有关。间变性星形细胞瘤和肥胖细胞型星形细胞瘤的恶性进展过程更快。

Objective To explore the relationship among the progression, histological types and pathology grade in recurrent astrocytoma. Methods The Clinical and pathological data of 54 cases of recurrent astrocytoma after the second operation were analyzed. Results The pathology grade of 28 cases was progressive and the rate was 51.9%. Anaplastic astrocytoma and gemistocytic astrocytoma showed more progressive and the rate were 66.7%, 78.6%, respectively. Conclusion The result suggested that the age pathology grade and histologyical types were all involved in the astrocytoma progression. Anaplastic astrocytoma and gemistocytic astrocytoma of adults were more progressive.