1[1]Jukka W, Veli-Matti K. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J, 1999, 13:781-792.
2[2]Johansson N, Ala-aho R, Uitto V, et al. Expression of collagenase-3(MMP-13) and collagenase-1(MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase. J Cell Sci , 2000, 113 pt 2:227-235.
3[3]Simon C, Hicks MJ, Nemechek AJ, et al. PD098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma. Br J Cancer, 1999, 80(9):1412-1419.
4[4]Vo HP, Lee MK, Crowe DL.alpha2beta1 integrin signaling via the mitogen activated protein kinase pathway modulate retinoic acid-dependent tumor cell invasion and transcriptional downregulation of matrix metalloproteinase 9 activity . Int J Oncol, 1998, 13(6):1127-1134.
5[5]Tsang KJ, Crowe DL. Retinoic acid and extracellular matrix metalloproteinase 9 expression is mediated by the mitogen activated protein kinase pathway. Int J Oncol, 2001, 18(2):369-374.
6[6]Bancroft CC, Chen Z, Dong G, et al. Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappaB signal pathways. Clin Cancer Res, 2001,7(2):435-442.
7[7]Yoshiji H, Kuriyama S, Ways DK, et al. Protein kinase C on the signaling pathway for vascular endothelial growth factor-mediated tumor development and angiogenesis. Cancer Res, 1999, 59(17):4413-4418.
8[8]Okajima E, Thorgeirsson UP. Different regulation of vascular endothelial growth factor expression by the ERK and p38 kinase pathways in V-ras, v-raf, and v-myc transformed cells. Biochem Biophys Res Commun, 2000, 270(1):108-111.
9[9]Harris VK, Coticchia CM, Kagan BL, et al. Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways. J Biol Chem, 2000, 275(15):10802-10811.
10[10]Zhou JN, Ljungdahl S, Shoushan MC, et al. Activating of tissue-factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway. Mol Carcinog, 1998, 21(4):234-243.
5Rabbani SA,Mazar AP.The role of the plasminogen activation system in angiogenesis and metastasis.Surg Clin North Am,2001,10(2):393-415.
6John A,Tuszynski G.The role of matrix metallop roteinases in tumor angiogenesis and tumor mestastasis.Pathol Oncol Res,2001,7 (1):14-23.
7Salh B,Marotta A,Matthewson C,et al.Investigation of the MekMAP Kinase-RSK pathway in human breast cancer.Anti-cancer Res,1999,19 (1 B):731-740.
8Mandell JW,Hussaini G,Zecevie M,et al.In situ visualization of intratumor growth factor signaling:immunohistochemical localization of activated ERK/MAP kinase in glial neoplasma.Am J Pathol,1998,153(5):1411-1423.
9Fromowitz FB,Violo MV,Chao S,et al.RAS p21 expression in the progression of breast cancer.Hum Pathol,1987,18 (12):1268-1275.
10Widmann C,Gibson S,Jarp MB,et al.Mitogen-activated protein kinase:conservation of a three-kinase module from yeast to human.Plysiol Rev,1999,79 (1):143-180.