1Kisel MA, Kulik LN, Tsybovsky IS, et al. Liposomes with phosphatidylethanol as a carrier for oral delivery of insulin: studies in the rat[J]. Iht Pharm, 2001,216(1-2):105.
2Watnasirichaikul S, Davies NM, Rades T, et al. Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions[J]. Pharm Res, 2000,17(6):684.
3Cunha AS, Grossiord JL, Puisieux F, et al. Insulin in w/o/w multiple emulsions: preparation characterization and determination of stability towards proteases in vifro[J]. J Microencapsul, 1997,14(3):311.
4Guo J, Ping Q, Zhang L. Transdermal delivery of insulin in mice by using lecithin vesicles as a carrier[J]. Drug Deliv, 2000.7(2): 113.
5Rao VU, Misra AN. Effect of permeation enhancers on transdermal absorption of insulin across human cadaver skin[J]. Drug Dev Iud Pharm,1994,20(16) :2585.
6Rao VU, Misra AN. Enhancement of iontophoretic permeation of insulin across human cadaver skin[J]. Pharmazie, 1994,49(7):538.
7Venugopalan P, Sapre A, Venkatesan N, et al. Pelleted bioadhesive polymeric nanoparticles for buccal delivery of insulin: preparation and characterization[J]. Pharmazie, 2001,56(3) :217.
8Nagareya N, Uchida T, Matsuyama K. Preparation and characterization of enteric microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method[J] . Chem Pharm Bull, 1998,46(10): 1613.
9Pillion DJ, Atochison JA, Gargiulo C, et al. Insulin delivery in nosedrops: new formulations containing alkyglycosisdes. Endocrinology,1995,135(6) :2386.
10Sasaki H, Tai C, Yamamura K, et al. Effect of preservatives on systemic delivery of insulin by ocular instillation in rabbits[J]. J Pharn Pharmacol, 1994,46:871.
4Cernea S, Kidron M . Comprison of pharmacokinetic and pharmacodynamic properties of single dose oral insulin spray and subcutaneous insulin injection in healthy subjects using the euglycemic clamp technique. Clin Ther,2004,26(12) :2084.
5Mcid S. insulin without injections draws closer. The Pharmaceutical Joumsl, 2005 ,27(10) :1562.
6Hussain A, Majumder QH, Ahsen F. Inhaled insulin is better Absorbed when Adminstered as a Drug Power Compared to Solution in the Prsence or Absence of Alkylglycosides. Pharm res, 2006, 23 ( 1 ) : 138.
7Harsch IA. Inhaled insulins: their potential in the treatment of diabetes mellitus. Treat Endocrinol, 2005,4 (3) : 131.
8Henry RR, Mudaliar SR, Howland WC ,et al. Inhaled insulin using the AERx Insulin Diabetes Management System in healthy and asthmatic subjects. Pharm Res, 2004,21(10) :1776.
9Selam JL. Inhaled insulin: clinical results in type 2 diabetic patients. Diabetes Care, 2001, 27(S)28.
10Knapczyk J,Lrowczynski L, Krzck J,et al. Requirements of chitosan for pharmaceutical and biomedical application. Elsevier, 1989,28 (2) :657.
