射频联合肝动脉栓塞化疗及无水酒精注射治疗不能手术切除的肝癌

RFA combined with TACE and ethanol injection for unresectable hepatic carcinoma

目的 探讨射频固化 (RFA )联合肝动脉化疗栓塞 (TACE )及无水酒精注射 (PEI)治疗不能手术切除的肝癌的效果。方法 对 41例肝癌应用RFA联合TACE及PEI治疗的临床资料进行回顾性分析。结果 原发性肝癌 (PHT) 3 0例 ,转移性肝癌 (MPT ) 11例。治疗后影像学显示病灶好转或稳定 2 6例。PHT 3 0例中治疗前甲胎蛋白阳性 16例 ,术后降至正常 12例。未发生严重并发症。结论 RFA联合TACE及PEI系一安全、可耐受 ,有效的新的综合治疗方法。可提高不能切除的肝癌的治疗效果。

Objective To explore the effect of radiofrequency ablation (RFA) combined with transcatherter arterial chemo-embolization (TACE) and percaulaneous ethanol injection (PEI) for unresectable hepatic malignancies. Methods The clinical data of 41 cases of unresectable liver cancer(URLC)treated by RFA,TACE and PEI were analysed retrospectively. Results There were 30 cases of primary hepatic cancer(PHT) and 11 cases of secondary hepatic cancer in this series.Ultrasound,CT and MRI showed the tumors shrinking or stable in 26 of the 41 patients postoperatively.AFP decreased to normal in 12 cases of 16 AFP positive PHT patients after operation. No severe complication was seen in the series. Conclusions RFA combined with TACE and PEI is a safe, well-tolerated and effective method for unresectable hepatic carcinoma, and may improve the treatment efficacy of URLC.