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发病时间对选择性经皮冠脉腔内成形术围术期左室功能的影响

Effect of history of coronary artery disease on left ventricular function peri-PTCA
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摘要 为观察冠心病发病时间对选择性PTCA围术期左室功能的影响,应用二维超声心动图(2DE),对成功地实施选择性经皮冠脉腔内成形术(PTCA)的25例患者,动态观察其围术期左室射血分数(LVEF)、每搏量(SV)、左室舒张末容积(LVEDV)及左室收缩末容积(LVESV)的演变。发现发病≤2a者围术期LVEF增加(P<005),LVEDV及LVESV缩小(分别P<005及P<001),SV无变化(P>005);发病>2a者虽有LVEDV及LVESV减少(均P<005),但LVEF及SV无变化(均P>005)。提示较早实施选择性PTCA者左室功能改善较明显;反映左室功能改善的2DE指标中。 To assess sequential changes in left ventricular ejection fraction (LVEF), stroke volume (SV), left ventricular end-disatolic volume (LVEDV) and left ventricular end-systolic volume (LVESV) during the subacute period after selective PTCA. We used quantitative two-dimensional echocardiography (2 DE) to examine 25 patients with coronary artery disease (CAD) at time of pre-and post-PTCA at 1~3 d, 7~10 d and 20~40 d. During peri-PTCA the patients with CAD history≤2 years showed significant improvement in LVEF ((P<0 05), significant decrease in both LVEDV and LVESV (P<0 05 and P<0 01, respectively), but no change in SV (P>0 05). And patients with the history >2 years showed significant decrease in both LVEDV and LVESV (both P<0 05), but no change in LVEF and SV (both P>0 05). The authors believe that CAD patients with the history≤2 years may respond better than those with the history>2 years during successful peri-PTCA. For assessing left ventricular function with 2 DE, LVEDV and LVESV are more sensitive than LVEF and SV.
出处 《武警医学》 CAS 1998年第9期11-13,共3页 Medical Journal of the Chinese People's Armed Police Force
关键词 经皮冠脉腔内成形术(PTCA) 发病时间 二维超声心动图(2DE) 左室功能 Percutaneus transluminal coronary angioplasty (PTCA) Left ventricular function History\ Two-dimensional echocardiography (2 DE)
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