摘要
目的 探讨微量白蛋白尿 (MA)与非糖尿病急性心肌梗死 (NDM AMI)患者预后的关系。 方法 收集 1996年 10月 2 0 0 1年 5月期间肾功能处于代偿期的NDM AMI住院病人 43例 ,分MA阳性组和MA阴性组 ,对入院后心肌梗死面积大小 (心电图、心肌酶谱分析 )、冠状动脉造影结果、AMI后 3月内心绞痛、再发心肌梗死、心衰发生率及死亡率进行统计学分析。 结果 NDM AMI患者MA阳性占 5 3 49% ,冠状动脉造影提示MA阳性组冠状动脉粥样硬化病变程度较MA阴性组广泛和严重 ;EKG和血清心肌酶谱显示MA阳性组心肌梗死面积大于MA阴性组 (P <0 0 5 ) ;两组AMI后 3月内心绞痛、再发心肌梗死、心衰发生率和死亡率具有显著性差异 (P <0 0 1)。 结论 MA阳性提示NDM AMI患者体内广泛性血管病变 。
Objective To investigate prognostic significance of microalbuminuria(MA) in non-diabetic acute myocardial infarction(NDM-AMI) patients. Methods 43 cases of AMI without renal insufficiency during 1996.10 to 2001.05 were divided into MA positive group and MA negative group.Statistical comparisons were conducted upon results of coronary angiography,occurrence rate of angina pectoris?acute myocardial re-infarction and heart dysfunction and mortality within 3 months after first AMI,together with analysis of electrocardiograph changes and myocardial enzymes. Results MA positive patients were about 53.49% in acute myocardial infarction;coronary angiography demonstrated that coronary atherosclerosis and stenosis in MA positive group was much more severe than that in MA negative group;there was a significant difference in EKG changes and serum level of myocardial enzymes between the two groups (P<0.05 ),frequency of occurrence of angina pectoris,acute myocardial re-infarction,heart dysfunction and mortality within 3 months after first AMI attack were markedly different between the two groups (P< 0.01 ). Conclusion Positive MA suggested diffuse vascular disease in patients with NDM-AMI and a poorer prognosis.
出处
《实用心脑肺血管病杂志》
2002年第4期195-198,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
