胰岛素样生长因子对骨的作用及运动对其的影响

Effects of Exercise on IGFs and IGFs on Bone

对胰岛素样生长因子系统 (IGFs)与骨形成、骨重建的关系以及运动对其的影响进行了综述和分析表明 ,IGF - 1,不仅可以促进成骨细胞的骨形成作用 ,还可促进破骨细胞的骨吸收作用 ,从而在骨的重建起着重要的作用 ;对于运动能否导致血清IGFs浓度升高 ,众多研究结果出现了分歧 ,这可能是由于研究方法 ,训练方式及运动强度不同所致 ,因此还需要对此进行更多更规范的研究以得出一个肯定的结果。

This article recounts the system of Insulin-like Growth Factors(IGFs) ,the relation between bone formation, bone rebuilding and the IGFs system and exercise' influence on it. IGFs, especially IGF-1, plays an important role in bone rebuilding, because it can not only stimulate the bone formation of osteoblast, but also the bone absorption of osteoclast. There is great divergence on whether exercise can add to serum IGFs concentrations. Different research methods, training styles and exercise intensity may explain it. Therefore more standard and more researches are needed to get a confirmative result.