骨欣肽(古欣肽)骨科临床应用106例分析

Analysis of Clinical Effect of Guxintai

目的 :观察骨欣肽 (古欣肽 )在治疗骨折、骨折不愈合、骨质疏松症及股骨头缺血性坏死的临床疗效。方法 :将 2 46例骨折、骨折不愈合、骨质疏松症及股骨头缺血性坏死的患者随机分为治疗组 ( 10 6例 )和对照组 ( 14 0例 ) ,治疗组应用骨欣肽 (古欣肽 ) ,通过 2组对比观察骨欣肽的临床疗效。结果 :骨折、骨折不愈合、骨质疏松症治疗组疗效优于对照组 ,优良率分别达到 87.5 %、73.7%、91.4%,经统计学处理 ,差异显著 (P <0 .0 5 )。而股骨头缺血性坏死 2组疗效无明显差异 ,但效果优良 (优良率分别为 87.5 %、71.4%) ,并分析其原因为所应用的臀中肌骨瓣与生物活性玻璃 (固骼生 )对股骨头缺血性坏死的治疗也有较好的疗效。结论 :骨欣肽 (古欣肽 )可加速骨折愈合 ,调节骨代谢 ,治疗骨折、骨折不愈合、骨质疏松症及股骨头缺血性坏死疗效确切 ,无明显不良反应 ,是骨科理想药物。

Objective:To analyze the clinical effect of Guxintai in treating fracture,fracture nonunion,osteoporosis,avascular necrosis of femoral head.Methods:246 patients suffered from fracture,fracture nonunion,osteoporosis,avascular necrosis of femoral head were randomly divided into two groups,the treating group(106 cases)and control group(146 cases).Guxintai was used in the treating group.Results:246 cases had been followed up for 5～24 months.The excellent and good rate in treating group of fracture,fracture nonunion,osteoporosis were 87.5%,73.7% and 91.4% respectively higher than that in control group (P<0.05).There was no obvious difference in treating and control group of avascular necrosis of femoral head.Conclusion:Guxintai has satisfactory effect in treating fracture,fracture nonunion,osteoporosis and avascular necrosis of femoral head.