2Henry D, McGettigan P. Epidemiology overview of gastr- ointestinal and renal toxicity of NSAIDs[J]. lnt J Clin Pract Suppl, 2003 (135) : 43.
3国家食品药品监督管理局.WSI-(X.01i)-200IZ布洛芬缓释片[S].2001.
4Neil R. Foster,Fariba Dehghani,Kiang M. Charoenchaitrakool,Barry Warwick.Application of dense gas techniques for the production of fine particles[J]. AAPS PharmSci . 2003 (2)
5Thompson C J,Hansford D,Higgins S,et al.Evaluation of ibuprofen-loaded microspheres prepared from novel copolyesters. InternationalJournal of Pharmaceutics . 2007
6Turk M,Upper G,Steurenthaler M,et al.Complex formation of Ibupro-fen andβ-Cyclodextrin by controlled particle deposition(CPD)usingSC-CO2. Journal of Supercomputing . 2007
7Hayball PJ.Chirality and nonsteroidal auti-inflammatory drugs. Drugs . 1996
8Neil R Foster,,Fariba Dehghan i,,K iang M,et al.Application ofdense gas techn iques for the production of fine particles. AAPSPharm Sci Tech . 2003
9Charoenchaitrakool M,Dehghani F,Foster NR.Utilization of supercritical carbon dioxide for complex formation of ibuprofen and methyl-β-cyclodextfin. International Journal of Pharmaceutics . 2002
