1例结肠癌肝转移患者多学科团队诊治与分析

Diagnosis and treatment of colonic cancer with synchronous liver metastases by a multidisciplinary team: a case report

目的探讨多学科团队(multidisciplinary team,MDT)在结直肠癌肝转移患者诊治过程中的作用。方法应用MDT(包括放射科、病理科、普外科、肝胆科、肿瘤科、放疗科)讨论的方式,对1例结肠癌肝转移患者整个治疗过程的不同时期进行全面评估及确立治疗方案,采用多学科综合治疗手段使患者得到最大程度获益。结果患者肝转移病灶潜在可切除,经转化治疗及多次多学科讨论后患者原发病灶及肝脏转移病灶接受手术及后续全身治疗,患者最终达到无瘤状态(no evidence of disease,NED),实现生存获益。结论 MDT模式可为结直肠癌患者找到最适合病情、多手段相结合、科学合理的诊疗方案,确保患者获得最佳治疗。

Objective To discuss the role of a multidisciplinary team(MDT)in the diagnosis and treatment of colorectal cancer with liver metastases.Methods A MDT involving specialists from the departments of radiology,pathology,general surgery,hepatobiliary surgery,oncology and radiotherapy participated in the treatment planning and assessment throughout the treatment in a case of colonic cancer with liver metastases.The patient received comprehensive treatments provided by the MDT to maximize the treatment benefits.Results Examination of the patient showed that the metastatic foci in the liver were resectable.After translational treatment and several rounds of multidisciplinary discussions,the patient received surgical resection of the primary and metastatic lesions with postoperative systemic treatments.Follow-up of the patient showed no evidence of disease after chemotherapy,and survival benefits were achieved from the treatments.Conclusion The multidisciplinary approach is capable of providing the patients with colorectal cancer with specific,precise and individualized treatments to maximize the treatment benefits.