摘要
为了评价维持量地高辛在慢性心力衰竭中的地位,本文对52例各类心脏病引起的慢性心衰病人进行维持量用药和停药的前瞻性研究,而对原来使用的利尿剂和/或血管扩张剂的用量基本不变,结果发现伴有室率快速的心房纤颤病人20例,19例停药1～2周后心室率平均增快26/分;14例出现心衰等级加重、而原来室率不快的心房纤颤病人7例,仅1例在停用地高辛后室率增快,重新出现心衰。对25例窦性心律的心衰病人,除2例心脏有明显扩大外,23例能安全撤药,没有引起严重血液动力学变化及临床心功能恶化。
For evaluating the importance
of oral maintenance dose of
Digoxin to treat the chronic congestive heart t failure because the
varied cardiac diseases,aprospective
study was performed in 25 patients
who have received and stopped the
drug with Out the change of the ad-
miniistration of the diuretic and/or
vasod-ilator The result showed that
19 of 20 patients who suffered from
the strial fibrillation was with hig-
her ventrical rate In 14 of these
patients with more severe heart fail-
ure'was found.
In 7 patients who suffered from
atrial fibriuation without the rapid
ventrical rate,only one of them rep-
eated the heart failure ofter stop
using Digoxin.with another group,23
of 25 patients who suffered from
the heart failure with sinus rhythmia
could be withdrawn safely without
severe hem odynamic variety and
deterioration of cardiac function
except 2 of such cases with the obvious
heart dilation.
