严重烧伤后早期营养支持途径对肝功能的影响

Effects of nutrition route on liver function at the initial stage of severe burn patients

目的考察严重烧伤早期营养支持途径对机体肝功能的影响。方法37例烧伤病人随机分为早期肠道营养组和肠外营养组，观察不同途径的营养支持两周后肝功指标的变化情况。结果严重烧伤后血清血清谷草转氨酶、碱性磷酸酶、乳酸脱氢酶均明显高于正常值，不同途径的营养支持两周，血清谷草转氨酶及血清碱性磷酶活性在伤后14d肠外营养组均明显高于肠道营养组(P< 0.05)。结论严重烧伤后病人出现不同程度的肝脏功能受损，肠外营养与肝脏功能的受损有关。

Objective This prospective study attempts to appraise effects of nutrition route on liver function at the initial stage of severe burn patients.Methods 37cases were collected and divided randomly into early enteral nutrition group(EN)and parenteral nutrition group (PN),liver function tests were investigated after two weeks .Result Serum glutmic oxaloacetic transaminase,alkaline phosphatase and lactate dehydrogenase were significantly higher than normal after burn injury ,on the 14th day postburn the level of serum glutamic oxaloacetic transaminase ,alkaline phosphatase and lactate dehydrogenase in PN group were significantly higher than that of EN group(P&lt; 0.05).Conclusion It is indicated that the liver function tests abnormalities were common at early stage of burn injury.There is obviously correlation between patenteral nutrition and liver function abnormalities.