摘要
自赤芝[Ganodermalucidum(Fr.)Karst]的二氯甲烷溶解部分分离得到一个新的三萜内酯化合物,命名为灵芝内酯(ganolactone)。根据光谱(UV,IR,1HNMR,13CNMR,MS和2DNMR)解析,确定其结构为1式。同时还从赤芝子实体中分到三个已知化合物,即灵芝醇A(ganoderiolA,2),灵芝醇B(ganoderiolB,3)和灵芝三醇(ganodermatriol4)。
A new triterpenoid, named ganolactone, was isolated from the CH 2Cl 2 soluble fraction of the fruiting body of Ganoderma lucidum. Its structure was deduced as 7β hydroxy 3,11,15 trioxo lanosta 8 en 24→20s lactone (1) on the basis of spectral analysis (UV, IR, MS. 1H NMR, 13 C NMR and 2D NMR) and was confirmed by X ray diffraction. In addition, three known compounds, ganoderiol A (2), ganoderiol B (3) and ganodermatriol (4), were obtained.
关键词
赤芝
灵芝内酯
三萜
Ganoderma lucidum
Triterpenoid
Ganolactone