Effects of Breviscapine on the Changes in Antioxidant Enzyme Activity Induced by Cerebral Ischemia-reperfusion in Rats

本文研究了灯盏花素对大鼠脑缺血再灌注引起抗氧化酶活性改变的影响，结果表明，灯盏花素明显提高脑缺血再灌注引起的脑组织超氧歧化酶（ＳＯＤ）、谷胱甘肽过氧化物酶（ＧＳＨｐｅｒｏｘｉｄａｓｅ）和过氧化氢酶（Ｃａｔａｌａｓｅ）的活性，减少脑组织丙二醛（ＭＤＡ）含量。这些作用有利于减轻脑缺血再灌注损伤。

\ Effects of breviscapine, the active ingredient isolated from Erigeron breviscapus (Vant) Handmazz, on the changes in antioxidant enzyme activity induced by cerebral ischemiareperfusion in rats were explored. It was found that breviscapine improved the activities of superoxide dismutase (SOD), GSHperoxidase and catalase, while decreasing the malondialdehyde (MDA) content in the brain, which was benificial in reducing the damage from cerebral ischemiareperfusion.