小剂量红霉素治疗早产儿喂养不耐受疗效观察

目的探讨小剂量红霉素治疗早产儿喂养不耐受的疗效。方法将54例出现喂养不耐受的早产儿随机分为治疗组31例和对照组23例。对照组给予保暖,抗感染,维持水电解质平衡,营养支持和对症治疗,治疗组在常规冶疗基础加小剂量红霉素3-5mg/kg.d,静脉滴注,1次/日,疗程5-7天。结果治疗组总有效率为83.87%,较对照组总有效率43.78%高(P<0.01),差异有统计学意义。结论小剂量红霉素治疗早产儿喂养不耐受有显著疗效,未见不良反应发生。

Objective To investigate the dose erythromycin treatment of feeding intolerance in premature children efficacy.Methods 54patients had feeding intolerance in preterm children were divided into treatment group and control group 31cases 23cases.In Control group the patients thermal insulation,anti-infection,the maintenance of water-electrolite balance,nutritional support and symptomatic treatment,In treatment group thepatients based on conventional medical treatments plus low-dose erythromycin 3-5mg/kg.d,intravenous infusion,1second/day,5-7days of treatment.Results The total effective rate was 83.87%,compared with the control group was 43.78%higher efficiency(P<0.01),the difference was statistically significant.Conclusion Low dose erythromycin treatment of feeding intolerance in premature children have significant effects,no adverse reactions.