对380例新发涂阳肺结核患者督导治疗效果分析

目的加强涂阳肺结核患者的治疗管理,提高2月末痰菌阴转率及疗末治愈率,为现代结核病控制策略提供新的治疗管理模式。方法选取2008年和2009年新发涂阳肺结核患者380例,采用2H3R3Z3E3/4H3R3方案治疗,分为村医和家庭成员督导治疗管理两组。在2月末、6月末进行痰涂片和X线胸片检查,观察治疗效果。结果两组2月末痰菌阴转率均为87%、疗末治愈率>91%,两组治疗效果无明显差别。结论家庭成员督导治疗管理的新发涂阳肺结核患者治愈率>91%,达到国家治愈率85%以上目标,是一种适宜贫困山区肺结核患者的督导治疗管理模式。

Objective to strengthen the management of patients with smear positive pulmonary tuberculosis,2sputum negative conversion rate and cure rate of treatment at the end,for the modern tuberculosis control strategy provides a new management mode.Methods from 2008 and 2009in the new smear positive pulmonary tuberculosis patients in 380 cases,treated by 2H3R3Z3E3/4H3R3regimen,divided into the village doctors and family members of the steering group management two.For sputum smear and chest X-ray examination in 2month,6month,observed the effect of treatment.Results The of two groups of 2sputum negative conversion rate was 87%,the cure rate was more than 91%at the end of treatment,there was no significant difference between the treatment effect of the two groups.Conclusion family supervision for the management of the new smear positive pulmonary tuberculosis patients cure rate of more than 91%,to achieve national cure rate of more than 85%goals,is suitable for impoverished and a mountainous area of pulmonary tuberculosis patients observed treatment management mode.