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β-catenin在支气管哮喘发病中作用机制研究进展

Research Progress of the Mechanism of Beta-catenin In the Pathogenesis of Bronchial Asthma
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摘要 β连环蛋白(β-catenin)是生物体内一种结构上高度保守的分子,在维持细胞间连接的完整性及细胞内信号转导中发挥着双重作用,β-catenin信号通路活化后促使β-catenin与TCF/LEF结合形成复合体,促进靶基因转录,参与肺的发育和维持内环境的平衡。 β catenin is a highly conserved molecular organism,plays a dual role in maintaining the integrity of the connection between cells and intracellular signal transduction,β-catenin signaling pathway activation stimulated β-catenin combine with TCF/LEF to form complex,promote the transcription of target genes involved in lung. The development and maintenance of the environment in the balance.
作者 梁世锋 庞宗东
机构地区 广西壮族自治区民族医院
出处 《大医生》 2017年第3期1-3,6,共4页 Doctor
关键词 Β-CATENIN 支气管哮喘 气道上皮细胞 β-catenin bronchial asthma airway epithelial cells
分类号 R562.25 [医药卫生—呼吸系统]
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大医生
2017年 第3期

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