沙丁胺醇联合布地奈德治疗小儿哮喘急性发作的效果分析

An Analysis of the Effect of Albuterol Combined with Budesonide in Treating Acute Asthma Attacks in Children

目的探讨沙丁胺醇联合布地奈德治疗小儿哮喘急性发作的效果分析。方法将2016年6月—2017年6月在云南省迪庆州香格里拉市虎跳峡镇中心卫生院儿科治疗的118例小儿哮喘急性发作患儿随机分为两组,对照组采用沙丁胺醇治疗,观察组采用沙丁胺醇联合布地奈德治疗,比较两组患儿的临床疗效、肺功能、症状改善时间。结果观察组治疗有效率为98.31%,明显高于对照组的79.66%,两组间有统计学差异(P<0.05);观察组治疗后FEV1、FEV1/FVC、PEER较对照组明显改善,两组间有统计学差异(P<0.05);观察组治疗后咳嗽、气喘、胸闷、痰鸣音消失时间明显短于对照组,两组间有统计学差异(P<0.05)。结论沙丁胺醇联合布地奈德治疗小儿哮喘急性发作效果显著,利于症状的快速改善,提高肺功能,具有积极的临床意义。

Objective to investigate the effect of salbutamol combined with budesonide for the treatment of acute asthma attacks in children. Methods in June 2016-June 2017 in our hospital pediatric treatment of 118 cases of children with acute attack of asthma children were randomly divided into two groups,control group adopts albuterol,observation group with salbutamol with budesonide therapy,comparing the clinical curative effect of two groups of children,pulmonary function,improve symptoms. Results the effective rate of observation group was 98.31%,significantly higher than 79.66% in the control group,and there was a statistical difference between the two groups(P<0.05). After treatment,FEV1,FEV1/FVC,and PEER were significantly improved compared with the control group,and there were statistically significant differences between the two groups(P<0.05). After treatment,the duration of cough,asthma,chest tightness and phlegm was significantly shorter than that of the control group,and there was a statistical difference between the two groups(P<0.05). Conclusion albuterol combined with budesonide is effective in the treatment of acute asthma attacks in children,which is conducive to the rapid improvement of symptoms and the improvement of pulmonary function,which has a positive clinical significance.