热毒宁注射液联合康复新液、阿昔洛韦膏治疗小儿手足口病临床疗效观察

Observation of Reduning Injection Combined with Kangfuxin Liquid, Acyclovir Ointment in the Treatment of Children with Hand Foot and Mouth Disease Clinical Curative Effect

目的研究热毒宁联合康复新液、阿昔洛韦膏治疗小儿手足口病的临床疗效及对肝功能和心肌酶谱的影响,为手足口病的治疗提供理论依据。方法选取2015年月—2016年宜昌市第三人民医院收治的100例手足口病患儿,将患儿随机分为对照组和治疗组,每组各50例,对照组患儿使用热毒宁注射液治疗,治疗组患儿在此基础上联合康复新液、阿昔洛韦膏治疗,对比两组患儿的临床疗效、临床症状恢复时间、住院时间差异。结果治疗组患儿治疗后治愈率及总有效率明显高于对照组(P<0.05),治疗组患儿在体温恢复正常时间、住院天数、口腔溃疡愈合时间、手足肛周疱疹恢复时间均显著少于对照组患儿(P<0.05)。结论热毒宁联合康复新液、阿昔洛韦膏治疗小儿手足口病效率提高,缩短患儿病程时间,同时可以显著减轻患儿拒食、流涎症状,在临床中值得推广。

Objective study on clinical effect of Reduning combined with Kangfuxin Liquid,acyclovir ointment in the treatment of children with HFMD,and provide theoretical basis for treatment of hfmd. Methods 100 cases of children with hand foot from 2015 years to 2016 in Yichang Third People's Hospital were mouth disease,patients were randomly divided into control group and treatment group,50 cases in each group,the control group using Reduning injection treatment,treatment group on the basis of this combined with Kangfuxin Liquid,acyclovir ointment treatment,clinical curative effect,compared with two groups of children recovery time of clinical symptoms,hospitalization time difference. Result the treatment group after treatment,the cure rate and the total efficiency was significantly higher than the control group(P<0.05),the treatment group in the body temperature recovery time,hospitalization time,healing time of oral ulcer,and perianal herpes recovery time were significantly less than in control group(P<0.05). Conclusion to improve the efficiency of Reduning combined with Kangfuxin Liquid and acyclovir ointment in the treatment of children with HFMD children,shorten the course of time,also can significantly relieve the children antifeedant,ptyalism,worthy of promotion in clinical practice.