摘要
目的探讨缬沙坦对冠心病伴舒张功能不全患者血浆NT-pro BNP和组织多普勒指标的影响探析。方法将2016年7月—2017年7月在该院心内科治疗的84例冠心病伴舒张功能不全患者随机分为两组,对照组采用常规治疗,在此基础上观察组使用缬沙坦,比较两组患者的临床疗效、血浆NT-pro BNP水平和组织多普勒指标变化。结果观察组治疗有效率为92.86%,明显高于对照组的80.95%,组间有统计学差异(P<0.05);观察组治疗后NT-pro BNP、LVEF、E、A、E/A、Em、E/Em较对照组明显改善,组间有统计学差异(P<0.05)。结论缬沙坦对冠心病伴舒张功能不全有良好疗效,能有效降低血浆NT-pro BNP水平,改善左心室舒张功能,具有积极的临床意义。
Objective To investigate the effects of valsartan with diastolic dysfunction in patients with plasma NT-pro BNP and tissue Doppler indices for coronary heart disease.Methods From July 2016 to July 2017,84 cases of coronary heart disease with diastolic dysfunction were randomly divided into two groups,the control group used the conventional treatment,the observation group used valsartan on on the basis of the clinical efficacy of two groups were compared,the change of serum NT-pro BNP level and tissue Doppler indices.ResultsThe effective rate of treatment group was 92.86%,significantly higher than the control group(80.95%),with a statistical difference(P<0.05);after treatment,NT-pro BNP,LVEF,E,A,E/A,Em,E/Em improved significantly in the observation group compared with the control group,with significant differences between the groups(P<0.05).Conclusion Valsartan has good effect on coronary heart disease patients with diastolic function,can effectively reduce the level of NT-pro BNP,improve the left ventricular diastolic function,which has a positive clinical significance.
出处
《大医生》
2017年第5期20-21,共2页
Doctor
