AECOPD患者下呼吸道感染中的细菌分布特点及耐药分析

Analysis of Bacterial Distribution and Drug Resistance in Lower Respiratory Tract infection of AECOPD Patients

目的探讨慢性阻塞性肺疾病急性加重(AECOPD)患者下呼吸道感染中的细菌分布特点及耐药性。方法以该院2014年1月—2016年1月收治的120例AECOPD患者为研究对象,将患者的痰液或呼吸道分泌物进行细菌培养鉴定与药敏试验,并对鉴定结果和试验结果进行分析。结果此次研究结果显示,分离出的病原菌患者有96例,分离到病原菌有138株,其中革兰阴性杆菌93株,革兰阳性球菌37株,真菌8株。结论 AECOPD患者的下呼吸道感染病原菌主要为革兰阴性菌,而且具有很强的耐药性,因此临床上在治疗AECOPD前,还应重视进行细菌培养和药敏试验,以便能够合理的选用抗菌药。

Objective To investigate the distribution characteristics and drug resistance of bacteria in lower respiratory tract infection in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods A total of 120 patients with AECOPD who were treated in our hospital from January 2014 to January 2016 were selected as the subjects.The sputum or respiratory secretions of patients were identified and tested for bacterial culture.The results were compared with those of the test results.Results There were 96 cases of pathogens isolated,138 strains were isolated from the pathogens,including 93 strains of Gram-negative bacilli,37 strains of Gram-positive bacteria and 8 strains of fungi.Conclusion AECOPD patients with lower respiratory tract infection pathogens mainly Gram-negative bacteria,and has a strong resistance,therefore,in clinical treatment of AECOPD,the bacterial culture and drug susceptibility testing should be focused to choose a reasonable antimicrobials.