前列地尔对合并糖尿病的冠心病患者介入治疗中造影剂肾病的预防作用研究

Preventive Effect of Alprostadil on Contrast-Induced Nephropathy in Patients with Coronary Heart Disease Complicated with Diabetes Undergoing Percutaneous Coronary Intervention

目的研究冠心病合并糖尿病患者介入治疗中应用前列地尔对造影剂肾病的预防效果。方法选取2014年3月—2017年3月本院收治的114例冠心病合并糖尿病患者,对照组采用常规水化疗法预防造影剂肾病,实验组口服前列地尔,观察对比两组造影剂肾病的发病率。结果实验组造影剂肾病发生率低于对照组(1.75%vs.10.53%,P<0.05)。结论前列地尔应用于冠心病合并糖尿病患者的介入治疗能有效降低造影剂肾病的发生率。

Objective To study the preventive effect of prealon in the treatment of patients with coronary heart disease and diabetes mellitus undergoing percutaneous coronary intervention. Methods From March 2014 to March 2017,114 patients with coronary heart disease and diabetes mellitus were included,the control group used conventional hydration therapy to prevent contrast nephropathy,while the experimental group orally taken Alprostadil. Results The incidence of nephropathy in the experimental group was lower than that in the control group(1.75% vs. 10.53%,P<0.05). Conclusion The incidence of nephropathy in patients with coronary heart disease and diabetes mellitus undergoing percutaneous coronary intervention was reduced effectively by Alprostadil.