晚期癌症老年患者姑息治疗的临床研究

Clinical Study on Palliative Treatment of Elderly Patients with Advanced Cancer

目的研究姑息治疗对晚期癌症老年患者的临床疗效。方法选取本院2014年6月—2016年4月收治的80例晚期癌症老年患者,将其平均分为两组,姑息组患者(n=40)进行姑息治疗,手术组患者(n=40)采用常规治疗。观察对比两组患者ESAS评分、SDS、SAS评分及一年生存期例数探讨其临床疗效。结果姑息组患者在疼痛、呼吸困难等症状评分均低于手术组(P<0.01),而在恶心、抑郁方面评分与手术组无显著差(P>0.05),乏力ESAS评分明显升高(P=0.01),姑息组一年生存期患者多于手术组(P<0.05)。姑息组患者SDS评分、SAS评分下降程度高于手术组(P<0.01)。结论姑息治疗可有效缓解晚期癌症老年患者的疼痛等症状,延长生存时间,疗效显著,全面提高患者的生活质量,值得进一步研究。

Objective To study the clinical efficacy of palliative treatment for elderly patients with advanced cancer. Methods Eighty elderly patients with advanced cancer in our hospital were included from June 2014 to April 2016,and equally divided into two groups:palliative therapy group(n=40)and conventional operation group(n=40).The ESAS,SDS,SAS scores and 1-year survival time of the two groups were observed and compared,and the clinical efficacy was discussed. Results Palliative patients in pain,breathing difficulties and other symptoms scores were lower than the surgery group(P<0.01),and the score in nausea,depression and surgery group had no significant difference(P>0.01),ESAS score increased significantly(P=0.01),1-year survival of patients in the palliative group was higher than that of the operation group(P<0.05). The scores of SDS and SAS in the palliative group were higher than those in the operation group(P<0.01). Conclusion Palliative treatment can effectively relieve the pain and other symptoms of elderly patients with advanced cancer,prolong the survival time,have a significant effect,and improve the quality of life of patients,which is worth further study.