连续性肾脏替代治疗在重症急性胰腺炎治疗过程中的应用

Application of Continuous Renal Replacement Therapy in the Treatment of Severe Acute Pancreatitis

重症急性胰腺炎(severe acute pancreatitis,SAP)是临床上常见的急危重症,以持续的器官功能衰竭为特点,病死率高,随着对SAP病理生理学机制的深入研究及探索,SAP的治疗已取得巨大进展,其中连续性肾脏替代治疗(continuous renal replacement therapy,CRRT)以其调节促炎及抗炎因子的平衡、减轻器官功能损害等作用而成为SAP患者的重要辅助治疗措施。本文就CRRT在SAP治疗中的应用做一综述。

Severe acute pancreatitis(SAP)is a common critical disease, which is characteristic of persistent multiple organ failure and high mortality rate. With the development of the study on the pathophysiologic mechanism of SAP,great progress on the treatment has been made. Continuous renal replacement therapy(CRRT)is one of them,which has become one of the important treatment measures for its effects,for example,regulating the balance of inflammatory and anti-inflammatory agents,reducing the effect of organ damage and etc.This review focus on the application of CRRT in the SAP therapy.