大剂量奥美拉唑联合奥曲肽治疗消化性溃疡合并上消化道出血的效果观察

Effect of High-Dose Omeprazole Combined with Octreotide on Peptic Ulcer with Upper Gastrointestinal Bleeding

目的观察大剂量奥美拉唑联合奥曲肽治疗消化性溃疡合并上消化道出血的效果。方法选取本院2014年3月7日—2016年3月8日收治的148例消化性溃疡合并上消化道出血患者,随机分为对照组与观察组,各74例,分别采用常规剂量奥美拉唑与奥曲肽(对照组)以及大剂量奥美拉唑与奥曲肽(观察组)进行治疗,对比两组治疗结果。结果观察组治疗效果高于对照组,对比差异显著(P<0.05)。结论大剂量奥美拉唑联合奥曲肽治疗消化性溃疡合并上消化道出血效果显著。

Objective To observe the application of high-dose omeprazole and octrexine in the treatment of peptic ulcer combined with upper gastrointestinal bleeding. Methods A total of 148 patients with peptic ulcer complicated with upper gastrointestinal hemorrhage admitted to our hospital from March 7,2014 to March 8,2016 were randomly divided into control group and observation group,74 cases in each group. The patients were treated with conventional omeprazole Azoles and octreotide(control group)and high-dose omeprazole and octreotide(observation group)were treated,the results of two groups were compared. Results The therapeutic effect of observation group was higher than that of control group,and the difference was significant(P<0.05). Conclusion High dose omeprazole + octrexine is effective in treating peptic ulcer with upper gastrointestinal hemorrhage.