老年人常见西药不良反应原因的分析及预防

Analysis and Prevention of Adverse Reactions of Common Western Drugs in the Elderly

目的探究导致老年人常见西药不良反应的原因、设计预防老年人常见西药不良反应的策略。方法以本院门诊西药房2015年9月—2016年9月内开具的893例处方为对照组,分析导致老年患者出现西药不良反应的原因,制定优化西药用药处方的干预性策略,以2016年10月—2017年10月开开具的1008例处方为实验组,探究处方干预在预防老年人常见的西药不良反应方面的效果。结果不同给药途径下,患者的不良反应发生情况比较差异显著;实验组患者的常见西药不良反应的发生率明显低于对照组患者,两组比较差异显著,P<0.05,有统计学意义。结论导致老年人常见西药不良反应的原因包括患者身体情况、给药途径、医师技能、患者用药等。应不断提高医师处方技能、加大患者健康教育力度,以避免患者出现不良反应。

Objective To explore the causes of common western medicine adverse reactions in the elderly and to design strategies to prevent the common adverse reactions of western medicine in the elderly. Methods A total of 893 prescriptions issued in our clinic from September 2015 to September 2016 were selected as the control group to analyze the causes of adverse drug reactions in elderly patients and to develop an intervention strategy to optimize the prescription of western medicine. With 2016 The 1008 prescriptions opened in October-October 2017 were selected as the experimental group to explore the effect of prescription interventions in preventing the adverse reactions of common western medicines in the elderly. Results The incidence of adverse reactions in patients with different routes of administration was significantly different;the incidence of common adverse drug reactions in the experimental group was significantly lower than that in the control group,with significant difference between the two groups(P<0.05,statistically significant).Conclusion Causes of common western drug adverse reactions in elderly people include the patient's physical condition,route of administration,physician skills,patient medication and so on. Should continue to improve the physician prescription skills,increase patient health education efforts to prevent patients with adverse reactions.