左旋甲状腺素钠治疗甲状腺手术后甲状腺功能减退症的临床研究

Clinical Study of L-Thyroxine in Treatment of Hypothyroidism after Thyroidectomy

目的研究左旋甲状腺素钠治疗甲状腺手术后甲状腺功能减退症患者的治疗剂量。方法选取2015年1月—2017年1月在本院接受手术治疗的甲状腺功能减退患者52例作为研究对象,按照手术方式分为两组,均采取左旋甲状腺素进行替代治疗,对比分析两组患者的治疗效果。结果两组患者使用左旋甲状腺素钠替代治疗的单位体重剂量与参考单位体重剂量相比差异显著(P<0.05),两组患者平均使用剂量之间的对比差异显著(P<0.05),具有统计学意义。两组患者组间男女合适替代治疗剂量对比差异无统计学意义。全切组男女合适替代治疗剂量与患者体重关系密切。结论对接受甲状腺切除术的甲状腺功能减退症患者治疗时,需要按照患者体内甲状腺的残留率以及体重来制定合适的替代治疗剂量。

Objective To study the appropriate replacement dose of levothyroxine sodium in hypothyroidism after thyroid surgery. Methods Fifty-two patients with hypothyroidism admitted to our hospital from January 2015 to January 2017 were enrolled in this study. The patients were divided into two groups according to the surgical procedure. All patients were treated with L-thyroxine for replacement therapy. treatment effect. ResultsThere was a significant difference between the two groups in the body weight dose and the reference body weight dose(P<0.05). The difference between the two groups was statistically significant(P<0.05). There was no significant difference in the dose comparison between the two groups of patients. The proper replacement dose of men and women in the full cut group was closely related to the weight of the patients. Conclusion For thyroid hypothyroidism patients undergoing thyroid resection,the need to follow the patient's thyroid residual rate and weight to develop a suitable alternative dose.