阿昔洛韦治疗儿童传染性单核细胞增多症的临床效果观察

Clinical Observation of Aciclovir in Treating Children's Infectious Mononucleosis

目的探讨阿昔洛韦治疗儿童传染性单核细胞增多症的临床疗效。方法对130例阿昔洛韦治疗儿童传染性单核细胞增多症的临床资料进行回顾性分析。结果传染性单核细胞增多症130例患儿中均有发热;伴肝功能损害ALT增高58例,占44.6%;伴鼻塞101例,占78%;伴眼睑浮肿者31例,占23.8%;伴皮疹16例,占12.3%;EB病毒IGM抗体阳性114例,占88%;予阿昔洛韦治疗,平均4.2 d后临床症状明显缓解。结论阿昔洛韦治疗传染性单核细胞增多症该病有较好的疗效。

Objective To investigate the clinical efficacy of aciclovir in the treatment of childhood infectious mononucleosis. Methods A retrospective analysis of clinical data of 130 cases of acyclovir in children treated with infectious mononucleosis was performed. Results There were fevers in 130 children with infectious mononucleosis;58 cases were associated with liver function impairment,accounting for 44.6%;101 cases with nasal congestion,accounting for 78%;31 cases with eyelid edema,accounting for 23.8%;With rash in 16 cases,accounting for 12.3%;EB virus IGM antibody positive 114 cases,accounting for 88%;to acyclovir treatment,the average 4.2 days after the clinical symptoms were significantly relieved. Conclusion Infectious mononucleosis is a systemic disease involving multiple systems. Acyclovir has a good effect on the disease.