急性肺栓塞患者的临床疗效及预后探讨

Clinical Effect and Prognosis of Acute Pulmonary Embolism

目的探讨急性肺栓塞患者的诊断和治疗。方法选取2014年10月至2017年10月本院收治的40例急性肺栓塞患者的临床资料,按是否在2周内明确诊断及治疗的方法分为两组,各20例。对照组2周内未明确诊断,仅给予对症治疗,观察组两周内明确诊断并给予溶栓抗凝治疗,比较两组患者的各项血气分析指标变化、疗效、预后。结果观察组治疗后呼吸、心率、Pa O2、Pa CO2、PAa O2与对照组比较差异有统计学意义(P<0.05);观察组治疗有效率为95.00%,显著高于对照组的70.00%(P<0.05)。结论急性肺栓塞患者早期的急诊诊断和溶栓治疗有确切临床效果,能有效改善肺组织血流灌注,提升肺通气功能,降低不良预后的发生率。

Objective To investigate the clinical effect and prognosis of emergency diagnosis and treatment of acute pulmonary embolism. Methods The clinical data of 40 patients with acute pulmonary embolism treated in our team from October 2014 to October 2017 were retrospectively analyzed. The patients were divided into two groups according to whether they were diagnosed and treated within 2 weeks. The control group included 20 patients. Without timely diagnosis and treatment, only symptomatic treatment was given. In the observation group, 20 cases were diagnosed and treated promptly. Thrombolytic anticoagulant therapy was given. Changes in blood gas analysis indexes, efficacy, and prognosis of the two groups were compared. Results Compared with the control group, the respiratory rate, heart rate, Pa O2, Pa CO2, and PA-a O2 were significantly improved in the observation group after treatment(P<0.05). The effective rate was 95.00% in the observation group, which was significantly higher than that in the control group(70.00%)the difference was statistically significant (P<0.05). Conclusion Early diagnosis and thrombolysis treatmengt in patients with acute pulmonary embolism have a definite clinical effect. It can effectively improve the perfusion of lung tissue, improve pulmonary ventilation, and reduce the incidence of adverse prognosis.