甘精胰岛素及门冬胰岛素30注射液治疗2型糖尿病的临床疗效及安全性比较

Clinical Efficacy and Safety of Insulin and Insulin 30 Injection in Treatment of Type 2 Diabetes Mellitus

目的比较甘精胰岛素及门冬胰岛素30注射液治疗2型糖尿病的临床疗效及安全性。方法选取本院收治的120例2型糖尿病患者作为研究对象,随机分为两组,各60例。A组给予甘精胰岛素注射治疗,B组给予门冬胰岛素30注射治疗,比较两组患者治疗效果与不良反应。结果治疗后,两组患者的空腹血糖和餐后2 h后血糖均明显降低,组间比较差异有统计学意义(P<0.05),不良反应发生情况明显较少,组间比较差异无统计学意义(P>0.05)。结论甘精胰岛素与门冬胰岛素30的治疗效果较好,并且使用两种药物进行治疗后出现不良反应现象的患者较少,因此在治疗中可以根据患者的情况选择合适的治疗药物。

Objective To compare the clinical efficacy and safety of insulin glargine and insulin aspart 30 injection in the treatment of type 2 diabetes mellitus.Methods A total of 120 patients with type 2 diabetes treated in our hospital were randomly divided into two groups,with 60 cases in each group A was given insulin glargine injection and group B was given insulin aspart 30 injection.The effect and adverse reactions were compared and analyzed.Results After treatment,both fasting blood glucose and postprandial blood glucose of the two groups were effectively reduced(P<0.05),and there was no significant difference between the two groups(P>0.05).Conclusion The treatment effect of insulin and insulin 30 are both better,and there are fewer patients with adverse reactions after the treatment with two drugs.Therefore,the appropriate treatment drugs can be selected according to the patient’s situation.