低分子肝素钠联合硫酸镁治疗妊娠高血压症的疗效

Effect of Low Molecular Weight Heparin Sodium Combined with Magnesium Sulfate on Pregnancy Induced Hypertension

目的观察低分子肝素钠联合硫酸镁治疗妊娠高血压症的疗效。方法选取本院收治的100例妊高症患者作为研究对象,随机分为两组,各50例。对照组实施硫酸镁治疗,实验组则实施硫酸镁联合低分子肝素钠治疗,比较两组妊高症患者治疗结果的差异性。结果实验组妊高症患者治疗后的D-二聚体水平显著低于对照组(P<0.05);两组治疗后的血压、平均动脉压水平均较治疗前有明显改善,其中实验组血压、平均动脉压水平改善程度显著优于对照组(P<0.05);实验组妊高症患者的不良反应率为4.00%,显著低于对照组(18.00%,P<0.05)。结论分子肝素钠与硫酸镁联合治疗妊高症安全有效。

Objective To observe the efficacy of low molecular weight heparin sodium combined with magnesium sulfate in the treatment of pregnancy induced hypertension(PIH). Methods Totally 100 patients with PIH were divided into two groups according to simple randomization.The control group was treated with magnesium sulfate and the experimental group was treated with low molecular weight heparin sodium. Results The D-dimer level of PIH patients in the experimental group was significantly lower than that in control group(P<0.05).After treatment,the blood pressure and mean arterial pressure of the two groups were better than those of the pre-treatment,and the improvement degree of the experimental group was better than that of the control group(P<0.05).The adverse reaction rate of the experimental group(4.00%)was significantly lower than that of the control group(18.00%),and the difference was statistically significant(P<0.05). Conclusion The combination of molecular heparin sodium and magnesium sulfate is safe and effective in the treatment of PIH.