期待治疗对早发型重度子痫前期合并胎儿生长受限妊娠结局的影响

Pregnancy Outcome of Expectant Treatment of Severe Preeclampsia with Fetal Growth Restriction

目的早发型重度子痫前期合并胎儿生长受限期待治疗的妊娠结局。方法选取本院收治的100例早发型重度子痫前期患者作为研究对象,依据有无合并胎儿生长受限分为观察组和对照组,各50例,比较两组孕产妇妊娠结局。结果合并组早产率显著高于非合并组(P<0.05);合并组患者产后出血及剖宫产、终止妊娠率与非合并组比较差异无统计学意义(P>0.05);合并组围生儿窒息与贫血以及心脏发育不全、死亡率均显著高于非合并组(P<0.05);孕周≥32周围生儿肺透明膜病发生率、心脏发育不全发生率、围生儿死亡率明显低于<30周,差异有统计学意义(P<0.05)。结论早发型重度子痫前期合并胎儿生长受限具有更高风险性,对产后产妇、胎儿造成严重影响。期待治疗可通过延长孕周改善胎儿结局,因此值得临床推广应用。

Objective To investigate the pregnancy outcomes of early severe severe preeclampsia combined with expectant treatment of fetal growth restriction. Methods A total of 100 patients with severe preeclampsia admitted to our hospital were included in the study. According to the presence or absence of fetal growth restriction,they were divided into a combined patients and a non-merged patients. A comparative analysis of maternal pregnancy outcomes in both groups was conducted. Results The premature delivery rate in the combined group was higher than that in the non-consolidated group(P<0.05). There was no difference in postpartum hemorrhage,cesarean section,and termination of pregnancy between the combined group and the non-consolidated group(P>0.05). Asphyxiation and anemia in the combined group,as well as cardiac hypoplasia and mortality were higher than those in the non-consolidated group(P<0.05). The incidence of hyaline membrane disease,cardiac dysplasia,and perinatal mortality were significantly lower in perinatal ≥32 gestational age children.<30 weeks,the difference was statistically significant(P<0.05). Conclusions Premature severe preeclampsia combined with fetal growth restriction is more risky and may have serious effects on postpartum mothers and fetuses. Expectant treatment can improve fetal outcomes by extending gestational age and is therefore worthy of clinical application.