益生菌联合序贯疗法治疗幽门螺杆菌相关性胃炎的临床疗效

Therapeutic Effect of Probiotics Combined with Sequential Therapy on Helicobacter pylori-Associated Gastritis

目的研究益生菌联合序贯疗法治疗幽门螺杆菌(Hp)感染相关性胃炎患者的临床疗效。方法选取本院接受治疗的150例Hp相关性胃炎患者作为研究对象,随机分为实验组和对照组,各75例。对照组患者接受序贯疗法,实验组患者在对照组的基础上联合益生菌治疗,比较两组患者临床疗效。结果治疗后,两组患者临床症状评分均明显降低,实验组显著低于对照组(P <0.05);两组患者不良发生率比较差异有统计学意义(P <0.05)。结论益生菌联合序贯疗法治疗Hp相关性胃炎具有良好地临床疗效。

Objective To study the clinical efficacy of probiotics combined with sequential therapy in the treatment of patients with Helicobacter pylori(Hp)infection-associated gastritis. Methods A total of 150 patients with Hp-associated gastritis who were treated in our hospital were divided into experimental group and control group by random data table method,75 patients in each group. The patients in the control group received sequential therapy. The patients in the experimental group were treated with probiotics on the basis of the control group. The clinical efficacy of the two groups was compared. Results After treatment,the clinical symptom scores of the two groups were significantly decreased,and those of the experimental group were more obviously. After treatment,the scores of the two groups were statistically significant(P<0.05). The incidence of adverse events in the two groups was statistically significant(P<0.05). Conclusion Probiotics combined with sequential therapy have a good clinical efficacy in the treatment of Hp-associated gastritis.