血清人绒毛膜促性腺激素与孕酮水平检验在早期先兆流产预测中的应用价值

Application Value of Serum Human Chorionic Gonadotropin and Progesterone Levels in Predicting Early Threatened Abortion

目的分析血清人绒毛膜促性腺激素(HCG)与孕酮水平检验在早期先兆流产预测中的应用价值。方法选取本院收治的100例单胎早孕孕妇作为研究对象,按照妊娠结局将其分为正常妊娠组(53例)、先兆流产组(31例)、难免流产组(16例)。3组均采用清晨空腹静脉血液作为检测样本,应用酶联免疫吸附时间对所有血清标本进行HCG和孕酮水平检测,观察3组孕妇HCG和孕酮水平。结果正常妊娠组HCG和孕酮水平最高、先兆流产组次之、难免流产组最低;联合检测特异性、敏感度、准确性均高于HCG和孕酮检测(P <0.05)。结论对于早期先兆流产预测应用HCG、孕酮联合检测能够有效提高诊断率,其较高的特异性、敏感度和准确性对临床诊断、治疗具有重要的指导价值。

Objective To analyze the value of serum human chorionic gonadotropin(HCG)and progesterone levels in predicting early threatened abortion. Methods A total of 100 women with early single pregnancy were selected and divided into normal pregnancy group(53 cases),threatened abortion group(31 cases)and inevitable abortion group(16 cases). The serum levels of HCG and progesterone were detected by enzyme-linked immunosorbent assay(ELISA)in all serum samples. The levels of HCG and progesterone in pregnant women were observed. Results HCG and progesterone levels were the highest in normal pregnancy group,followed by threatened abortion group,and the lowest in inevitable abortion group. The specificity,sensitivity and accuracy of combined detection were higher than those of HCG and progesterone detection(P<0.05). Conclusion The combined detection of HCG and progesterone can effectively improve the diagnostic rate of threatened abortion,and its high specificity,sensitivity and accuracy have important guiding value for clinical diagnosis and treatment.