新生儿红斑狼疮的临床特点及病例资料分析

Clinical Features and Case Analysis of Neonatal Lupus Erythematosus

目的分析新生儿红斑狼疮的临床特点及病例资料。方法选择2015年1月至2017年12月本院收治的10例住院治疗的红斑狼疮患儿,分析患儿临床特点,统计患儿免疫血清学指标,随访治疗效果。结果 10例红斑狼疮患儿中有6例患儿母亲确诊为系统性红斑狼疮,3例确诊为干燥综合征,1例确诊为结缔组织病;所有患儿给予激素治疗白细胞恢复正常,Ⅲ度房室传导阻滞患儿治疗无效。结论观察患儿皮肤和实验室检测指标可以确诊患儿红斑狼疮,确定疾病具自限性,预后较好。

Objective To analyze the clinical features and case data of neonatal lupus erythematosus(SLE). Methods Ten cases of lupus erythematosus hospitalized in our hospital from January 2015 to December 2017 were selected as the subjects. The clinical characteristics of 10 cases were analyzed,and the serological indexes of children were analyzed,and the therapeutic effect was followed up. Results In 10 cases of lupus,6 cases' mothers were diagnosed as systemic lupus erythematosus,3 were diagnosed as Sjogren's syndrome,and 1 were diagnosed as connective tissue disease. All children received hormone treatment,and the white blood cells returned to normal. Conclusion The diagnosis of children with lupus erythematosus can be confirmed by observing the test indexes of the skin and Laboratory of the children. The disease is self limiting and the prognosis is good.